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Clostridium difficile

C. difficile increases mortality, colectomy, complication risk in UC

Healio - ‎Apr 28, 2016‎
Clostridium difficile infection results in a poorer prognosis among patients newly diagnosed with ulcerative colitis, as it increases their risk for colectomy, postoperative complications and death, according to a population-based inception cohort study.

Isolation of Clostridium difficile-carriers linked to lower hospital transmission

2 Minute Medicine - ‎Apr 26, 2016‎
1. Screening for and isolating carriers of Clostridium difficile at admission to hospital was associated with lower rates of healthcare-associated C. difficile infection (HA-CDI) at a single institution in Quebec, CA. 2. A multi-center study would be ...

Effort to detect, isolate asymptomatic C. difficile carriers linked to lower incidence

Science Daily - ‎Apr 25, 2016‎
An intervention at a Canadian acute care facility to screen and isolate asymptomatic Clostridium difficile carriers was associated with decreased incidence of health-care associated C. difficile infection, a finding that needs to be confirmed in ...

Isolating Asymptomatic C diff Carriers May Reduce Incidence

Medscape - ‎Apr 26, 2016‎
Screening for and isolating asymptomatic Clostridium difficile carriers appears to have cut the number of infections in half at the Heart and Lung Institute, a 354-bed Canadian tertiary institution in Québec City, Québec, Canada, researchers say.

Inhibitory Activity of Systemic Antibiotics Against Clostridium difficile

Infection Control Today - ‎Apr 20, 2016‎
Systemic antibiotics vary widely in in vitro activity against Clostridium difficile. Some agents with activity against C. difficile (e.g., piperacillin/tazobactam) inhibit establishment of colonization in mice. Kundrapu, et al. (2016) tested the ...

Secondary bile salts may be novel biomarkers of C. difficile recurrence

Healio - ‎Apr 26, 2016‎
Patients with recurrent Clostridium difficile infection had distinct bile acid and microbiome profiles compared with healthy controls and patients with first Clostridium difficile infection, according to research published in Alimentary Pharmacology ...

Detecting, isolating C. difficile carriers associated with reduced incidence of hospital-acquired infections

Healio - ‎Apr 27, 2016‎
Screening and isolating asymptomatic Clostridium difficile carriers was associated with lower incidence of health care-associated C. difficile infections at an acute care facility in Canada, according to research published in JAMA Internal Medicine.

Detecting, Isolating C. difficile Carriers Beneficial

Doctors Lounge - ‎Apr 26, 2016‎
Detecting and isolating Clostridium difficile carriers can reduce the incidence of health care-associated C. difficile infection, according to a study published online April 25 in JAMA Internal Medicine.

Probiotika og tilførte tarmbakterier kan forebygge infeksjon

Nasjonalt kunnskapssenter for helsetjenesten - ‎Apr 27, 2016‎
Bakterien Clostridium difficile er en av de hyppigste årsakene til sykehusrelatert diaré. Symptomene skyldes endringer av tarmens normale bakterieflora på grunn av antibiotikabehandling.

Impfung gegen Clostridium difficile

APOTHEKE ADHOC - ‎Apr 25, 2016‎
Krankenhauskeime sind ein zunehmendes Problem in den Industrieländern, da sich vermehrt Antibiotikaresistenzen entwickeln. Das anaerobe Bakterium C. difficile ist eine der Hauptursachen von Infektionen in Krankenhäusern und Pflegeeinrichtungen.

Hospital Visitors and Isolation Precautions: Clearing Up the Confusion

Medscape - ‎8 hours ago‎
Evidence supports the use of standard and contact isolation precautions of healthcare workers. However, the role of visitors in transmitting or becoming infected in acute care hospitals is not known.

Report: Antibiotic stewardship programs lower infections, improve care

CIDRAP - ‎Apr 28, 2016‎
Vibra Hospital of Northern California in Redding, Calif., and Sharp Villa Coronado Long-Term Care Facility in Coronado, Calif., were able to obtain support for nascent ASPs after linking antibiotic use to increases in healthcare-associated Clostridium ...

Student Research, Creativity, Innovation on Display at Annual Conference

UVM News - ‎2 hours ago‎
She'll be attending the UVM College of Medicine this fall, following her impressive work as lead author on a study published by the Journal of Bacteriology that contributes to a better understanding of the notoriously difficult to treat Clostridium ...

New study expands potential applications for stool transplants

Medical Xpress - ‎Apr 28, 2016‎
The approach has been very successful for treating recurrent Clostridium difficile (C. diff) infections - which can cause life-threatening cases of diarrhoea, and are becoming a serious problem in hospitals and healthcare institutes.

Transplanted Fecal Microbes Stick Around

The Scientist - ‎Apr 28, 2016‎
FMTs, in which stool microbes from a healthy donor are transplanted into a recipient, have been shown to be a successful treatment for recurrent Clostridium difficile infection, and are being investigated for a number of other gastrointestinal ...

News Scan for Apr 26, 2016

CIDRAP - ‎Apr 26, 2016‎
Screening patients at hospital admission for asymptomatic Clostridium difficile (C diff) and isolating those found to be carriers lowered the incidence of healthcare-associated C diff infection by more than 60% and may be a promising strategy for ...

Mixed News on Hospital Infections

JAMA: The Journal of the American Medical Association - ‎Apr 26, 2016‎
Depending on the setting, antibiotic-resistant bacteria cause more than 1 in 4 health care–associated infections excluding C difficile, the investigators noted. They stressed that antibiotic stewardship programs are vital to preventing infections and ...

News briefs

Kansas State Collegian - ‎Apr 19, 2016‎
“AMS parents/guardians - A staff and student at Anthony Middle school have had confirmed cases of Clostridium Difficile,” Kline said.
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Cedars-Sinai Scores a 'C' in Medical Center Safety Study

WEHOville - ‎Apr 28, 2016‎
Clostridium difficile infection. C. diff is a bacterium that can cause diarrhea, abdominal pain, loss of appetite, and fever, the Hospital Safety Score report says.

Antimicrobial Stewardship: A Local Imperative

Medscape - ‎Apr 27, 2016‎
... antimicrobial use included having at least one full-time infectious diseases (ID) physician (-3%), an ID fellowship program (-9%), an ID-trained pharmacist (-10%), and a policy to address antimicrobial use in patients with Clostridium difficile ...
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